SMab® (Single Cell-Based Monoclonal Antibody Discovery Platform) is an antibody discovery and development platform based on single B cell. This technology follows steps including single-cell sorting, culturing, and gene cloning of specific antibodies to produce high-quality and -specific recombinant antibodies. By incubating single B cell in optimized culture media for several weeks in vitro, the B cells can be stimulated and proliferate in vitro, then secrete enough IgG in the supernatant for primary screening.